Burning Mouth Syndrome (BMS) is a complex condition thought to be of neuropathic origin, meaning it arises from nerve dysfunction. It is characterized by burning or tingling sensations in the mouth, lips, and tongue. Other symptoms may include dry mouth, numbness, and impaired taste, though the presentation varies significantly from person to person.

BMS affects approximately 2-4% of the population, with women being seven times more likely to develop it than men. It is especially prevalent in postmenopausal women, with most cases occurring between the ages of 50 and 79 years.

Burning Mouth Syndrome is primarily a diagnosis of exclusion, meaning that other potential causes—such as Sjogren’s syndrome, oral lesions, medication side effects, and systemic diseases—must first be ruled out.

BMS can persist for months or even years, and in some cases, it may never fully resolve.

Several classes of medications can be used to treat BMS, including:
✅ Antidepressants
✅ GABAergic medications
✅ Analgesics
✅ Antipsychotics